SKP2B OVEREXPRESSION ALTERS A PROHIBITIN-P53 AXIS AND THE TRANSCRIPTION OF PAPP-A, THE PROTEASE OF INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 4.

Skp2B overexpression alters a prohibitin-p53 axis and the transcription of PAPP-A, the protease of insulin-like growth factor binding protein 4.

We previously reported that the degradation of prohibitin by the SCF(Skp2B) ubiquitin ligase results in a defect in the activity of p53.We also reported that MMTV-Skp2B transgenic mice develop mammary gland Suspension Shock Absorber Wrench tumors that are characterized by an increased proteolytic cleavage of the insulin-like growth factor binding p

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Moral Injury and Suicide Ideation Among Combat Veterans: The Role of Trauma-Related Shame and Collective Hatred

Introduction Exposure to potentially morally injurious events (PMIEs) among combat veterans has been acknowledged as a significant stressful combat event that may lead to mental health problems, including suicide ideation (SI).Several Sports Repair Labor - Sharpening - Skates studies have examined the risk and protective factors that can explain th

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Gender differences in the predictive role of self-rated health on short-term risk of mortality among older adults

Objectives: Despite the well-established association between self-rated health and mortality, research findings have been inconsistent regarding how men and women differ on this link.Using a national sample in the United States, this study compared American male and female older adults for the predictive role of baseline self-rated health on the sh

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